Senior Management

Stephen L. Holcombe, B.Sc
President, Chief Executive Officer
Stephen L. Holcombe, B.Sc
President, Chief Executive Officer


Mr. Holcombe received his Bachelor of Science degree in accountancy from Wake Forest University. Mr. Holcombe brings over 23 years of financial and managerial experience to vTv Therapeutics. Over that time Mr. Holcombe has primarily been involved as an executive officer with early stage companies focusing on the execution of private and public financings, developing corporate alliance and partnership strategies and managing relationships with external constituents. From 1978 to 1985 he served in... 
Rudy Howard, B.A., CPA
Executive Vice President, Chief Financial Officer
Rudy Howard, B.A., CPA
Executive Vice President, Chief Financial Officer


Mr. Howard brings over 30 years of senior management experience to vTv Therapeutics. Prior to joining the Company, Mr. Howard served as Chief Financial Officer of SciQuest, Inc., an international spend management software company. Before joining SciQuest, he was CFO of MDS Pharma Services, a multi-national pharmaceutical services organization. He has also served as CFO for a number of other public and private multi-national companies in the life sciences and software industries, including Pharma... 
Robin E. Abrams, J.D.
Executive Vice President, General Counsel
Robin E. Abrams, J.D.
Executive Vice President, General Counsel


Robin Abrams joined vTv Therapeutics as Executive Vice President, General Counsel in July, 2016. Ms. Abrams also serves as General Counsel and Chief Administrative Officer at SIGA Technologies Inc.

Prior to joining vTv, Ms. Abrams had a fourteen-year tenure at Purdue Pharma L.P., where she served as Vice President and Associate General Counsel. While at Purdue, Ms. Abrams was Purdue’s primary legal contact with government entities including the Department of Justice, Drug Enforcement ... 
Carmen Valcarce, Ph.D.
Executive Vice President, Chief Scientific Officer
Carmen Valcarce, Ph.D.
Executive Vice President, Chief Scientific Officer


Dr. Valcarce obtained her Ph.D. at the Universidad Autonoma de Madrid, Spain in 1988 under the direction of Prof. Jose M. Cuezva in the field of metabolic diseases with focus on mitochondrial development and maturation after birth. From 1989 to 1998 Dr. Valcarce completed her postdoctoral studies and held the position of Assistant Professor at the Department of Clinical Chemistry at Lund University, Sweden under the direction of Prof. Johan Stenflo. During this time, the focus of her research wa... 
Aaron Burnstein, PharmD
SVP, Clinical Development
Aaron Burnstein, PharmD
SVP, Clinical Development


Dr. Aaron Burstein obtained his BS and Pharm.D. degrees from the State University of New York at Buffalo. Dr. Burstein completed his post-doctoral research fellowship at the Dent Neurologic Institute where his training focused on investigational treatments for neurologic disorders, including stroke and epilepsy, as well as on pharmacokinetic/pharmacodynamic data analysis techniques.

He subsequently held an Assistant Professor appointment at the University of Maryland School of Phar... 
Robert C. Andrews, Ph.D.
SVP Chemistry, Pharmaceutical Development and Quality
Robert C. Andrews, Ph.D.
SVP Chemistry, Pharmaceutical Development and Quality


Dr. Andrews obtained his Ph.D. at the University of South Carolina in 1986 under the direction of Prof. James Marshall and completed postdoctoral studies in 1988 with Prof. Albert Meyers at Colorado State University. Dr. Andrews joined Glaxo Research and Development in 1988, pursuing orally active phospholipase A2 inhibitors and therapeutic agents for benign prostatic hyperplasia (BPH). With Glaxo Wellcome Dr. Andrews progressed to the area of proteases and his team discovered potent inhibitors ... 
Imogene Dunn, Ph.D.
SVP, BioMetrics and Regulatory
Imogene Dunn, Ph.D.
SVP, BioMetrics and Regulatory


Imogene Dunn, Ph.D., has more than 25 years of experience in data science services (including data management, biostatistics, and applications of information technology to the clinical development process) and also in regulatory affairs. A key focus of her career has been regulatory data sciences, leveraging progressive methodologies compliant with regulatory expectations while assuring integrated analyses and data files are suitable for registration packages.

Prior to joining vTv T... 
Samuel B. Rollins, Ph.D.,J.D.
SVP, Intellectual Property
Samuel B. Rollins, Ph.D.,J.D.
SVP, Intellectual Property


Dr. Rollins earned a Bachelor of Science degree in Chemistry from the University of North Carolina at Chapel Hill and a Ph.D. in Chemistry from Colorado State University under the direction of Prof. Robert M. Williams. His doctoral thesis was directed to the design and stereocontrolled synthesis of an eight-membered ring precursor to a photo-triggered mitosene. Following graduate school, Dr. Rollins earned a Juris Doctorate from Wake Forest University School of Law and practiced patent law at Ki...