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|vTv Therapeutics to Present Two Posters at the American Diabetes Association’s 77th Scientific Sessions|
Details of the presentations are listed below:
Late-Breaking Poster title: “Is Less More? Learning to Dose the
Oral, Non-peptide GLP-1R Agonist, TTP273 in Type 2 Diabetics”
Poster title: “TTP273, Oral (Non-peptide) GLP-1R Agonist:
Improved Glycemic Control without Nausea and Vomiting in Phase 2”
“We look forward to providing an update on TTP273, one of vTv’s lead
diabetes compounds, at the American Diabetes Association’s 77th
Scientific Sessions,” said
TTP273 is an investigational, orally dosed small molecule that works by activating the GLP-1 receptor. Activation of the GLP-1 receptor leads to the enhancement of insulin secretion and suppression of glucagon production and decreased food intake. There are currently several marketed injectable GLP-1 therapies. These agents have demonstrated notable glucose lowering in addition to weight loss; however, their widespread use may be hindered by the route of administration (injection) and by the high incidence of gastrointestinal side effects (nausea and vomiting).
About Type 2 Diabetes
Type 2 diabetes is a result of the body’s inability to use insulin
properly to control sugar in the bloodstream. Type 2 diabetes represents
up to 95% of diabetes patients, imposing a growing burden on healthcare
systems globally. Diabetes remains the 7th leading cause of death in
About vTv Therapeutics
vTv Therapeutics Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of orally administered small molecule drug candidates to fill significant unmet medical needs. vTv has a pipeline of clinical drug candidates led by programs for the treatment of Alzheimer’s disease and Type 2 diabetes as well as treatment of inflammatory disorders and the prevention of muscle weakness.
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