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<!-- Creation Date      : 2021-05-05T13:57:37.7242582+00:00 -->
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<!-- Copyright (c) 2021 Donnelley Financial Solutions, Inc. All Rights Reserved. -->
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  <xsd:element id="vtvt_TypeTwoDiabetesMember" name="TypeTwoDiabetesMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_PeriodUsedToDetermineExchangeValueBasedOnWeightedAveragePriceOfClassCommonStock" name="PeriodUsedToDetermineExchangeValueBasedOnWeightedAveragePriceOfClassCommonStock" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_RedeemableNonControllingInterestExchangeAgreementStockConversionRatio" name="RedeemableNonControllingInterestExchangeAgreementStockConversionRatio" type="xbrli:pureItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_ExchangeOfRedeemableNonControllingInterestToClassACommonStockMember" name="ExchangeOfRedeemableNonControllingInterestToClassACommonStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_RedeemableNoncontrollingInterestTemporaryEquityRedemptionValue" name="RedeemableNoncontrollingInterestTemporaryEquityRedemptionValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="vtvt_AggregateOfferingPriceOfShares" name="AggregateOfferingPriceOfShares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="vtvt_AtTheMarketOfferingMember" name="AtTheMarketOfferingMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_OwnershipPercentageOfMajorityOwner" name="OwnershipPercentageOfMajorityOwner" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_CommitmentContingencyAndRelatedPartyTransactionsAbstract" name="CommitmentContingencyAndRelatedPartyTransactionsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_MacAndrewsAndForbesIncorporatedMember" name="MacAndrewsAndForbesIncorporatedMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_LetterAgreementsExpirationDate" name="LetterAgreementsExpirationDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_ClassOfWarrantOrRightWarrantsExpirationDate" name="ClassOfWarrantOrRightWarrantsExpirationDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_ClassOfWarrantOrRightNumberOfSharesIssuedForWarrantsOrRights" name="ClassOfWarrantOrRightNumberOfSharesIssuedForWarrantsOrRights" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_ClassOfWarrantOrRightNumberOfRemainingSharesToBeIssued" name="ClassOfWarrantOrRightNumberOfRemainingSharesToBeIssued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="vtvt_TwoThousandAndNineteenLetterAgreementMember" name="TwoThousandAndNineteenLetterAgreementMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_PercentageOfAmountOfCashSavings" name="PercentageOfAmountOfCashSavings" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_TaxReceivableAgreementDescription" name="TaxReceivableAgreementDescription" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="vtvt_IncomeTaxesLineItems" name="IncomeTaxesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_IncomeTaxesTable" name="IncomeTaxesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_MFTTPHoldingsLLCMember" name="MFTTPHoldingsLLCMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_NetIncomeLossAvailableToCommonStockholdersBasicAndDiluted" name="NetIncomeLossAvailableToCommonStockholdersBasicAndDiluted" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="vtvt_ScheduleOfEarningsPerShareLineItems" name="ScheduleOfEarningsPerShareLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_ScheduleOfEarningsPerShareTable" name="ScheduleOfEarningsPerShareTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_EmployeeStockOptionsUnderLetterAgreementsMember" name="EmployeeStockOptionsUnderLetterAgreementsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_FairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisLineItems" name="FairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_FairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisTable" name="FairValueOfAssetsAndLiabilitiesMeasuredOnRecurringBasisTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_WarrantLiabilityRelatedPartyMember" name="WarrantLiabilityRelatedPartyMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisWarrantLiabilityIssuance" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisWarrantLiabilityIssuance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="vtvt_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisWarrantLiabilitySales" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisWarrantLiabilitySales" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="vtvt_LetterAgreementWarrantsMember" name="LetterAgreementWarrantsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="vtvt_ProceedsFromIssuanceOfCommonStockGross" name="ProceedsFromIssuanceOfCommonStockGross" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
</xsd:schema>
